Article
Molecular characterization of the iron-hydroxamate uptake system in Staphylococcus aureus.
Applied and environmental microbiology - 1 Feb 2001
Cabrera G, Xiong A, Uebel M, Singh V K, Jayaswal R K
Abstract excerpt
To investigate iron uptake, a chromosomal locus containing three consecutive open reading frames, designated fhuC, fhuB, and fhuD, was identified in Staphylococcus aureus. Whereas the fhuC gene encodes an ATP-binding protein, fhuB and fhuD code for ferrichrome permeases and thus resemble an ATP-binding cassette transporter. A fhuB knockout mutant showed impaired uptake of iron bound to the siderophores but not of...
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