Article
Association between genetic polymorphisms of cytochrome P450 2C19 and the risk of cerebral ischemic stroke in Chinese.
BMC medical genetics - 17 Jul 2014
Gu Shuzhen, Sun Yan, Han Ruifa, Wang Lin, Wang Dongliang, Wang Jizuo, Li Xin
Abstract excerpt
BACKGROUND: Cytochrome P450 (CYP) 2C19 is a very important drug metabolizing enzyme. Although the single nucleotide polymorphisms (SNPs) of CYP2C19 G681A and G636A have been suggested that they may increase the incidence of cardiovascular events, the relationship between SNPs in CYP2C19 and cerebral ischemic stroke (CIS) are unclear. The aim of this study was to investigate the correlation between the...
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