Article
CYP1B1 Genetic Variants (rs10916 and rs2855658) Are Associated with Increased Risk of Ischemic Stroke in Chinese Han Population.
Cerebrovascular diseases (Basel, Switzerland) - 1 Jan 2023
Zhang Fan, Fu Chuanyi, Deng Yidong, Zhang Mao, Peng Hao, Li Wenan, Zhong Jian, Zhou Qing, Huang Li, Xiao Shuli, Zhao Jiannong
Abstract excerpt
INTRODUCTION: Ischemic stroke (IS) is an extremely complex disease caused by the combined action of multiple environmental and genetic factors. CYP1B1 is a member of the cytochrome P450 protein family, and it is an important human drug-metabolizing enzymes. We aimed to explore the association between CYP1B1 genetic variants and IS risk in Chinese Han population. METHODS: We recruited 1,150 participants to conduct...
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