Article
Association of ADH1B polymorphism and alcohol consumption with increased risk of intracerebral hemorrhagic stroke.
Journal of translational medicine - 29 May 2021
Lin Chun-Hsiang, Nfor Oswald Ndi, Ho Chien-Chang, Hsu Shu-Yi, Tantoh Disline Manli, Liaw Yi-Chia, Daria Mochly-Rosen, Chen Che-Hong, Liaw Yung-Po
Abstract excerpt
BACKGROUND: Alcohol consumption is one of the modifiable risk factors for intracerebral hemorrhage, which accounts for approximately 10-20% of all strokes worldwide. We evaluated the association of stroke with genetic polymorphisms in the alcohol metabolizing genes, alcohol dehydrogenase 1B (ADH1B, rs1229984) and aldehyde dehydrogenase 2 (ALDH2, rs671) genes based on alcohol consumption. METHODS: Data were...
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