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Article

Association of the ENPP1 K121Q polymorphism with susceptibility to type 2 diabetes in different populations: evidence based on 40 studies.

Endocrine journal - 1 Jan 2014

Tang Song-Tao, Shen Xin-Ru, Tang Hai-Qin, Wang Chang-Jiang, Wei Wei, Zhang Qiu, Wang Yuan

Abstract excerpt

The K121Q gene polymorphism of ectoenzyme nucleotide pyrophosphate phosphodiesterase 1(ENPP1) has been widely investigated, however, results have been somewhat conflicting. The aim of this meta-analysis was to establish a precise estimation of the association between ENPP1 gene polymorphisms and type 2 diabetes (T2D). A literature search in PubMed, Embase, Cochrane Library and China Biology Medicine (CBM)...

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Source

Identifiers

PMID: 25109753
DOI: 10.1507/endocrj.ej14-0272

Genes

ENPP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Association of the ENPP1 K121Q polymorphism with susceptibility to type 2 diabetes in different populations: evidence based on 40 studies.PMID 25109753Read ↗

ENPP1 K121Q polymorphism and type 2 diabetes mellitus in the Chinese population: a meta-analysis including 11,855 subjects.Semantic proximity Read ↗

The ENPP1 K121Q polymorphism is associated with type 2 diabetes in European populations: evidence from an updated meta-analysis in 42,042 subjects.Semantic proximity Read ↗

Association between the ENPP1 K121Q polymorphism and risk of diabetic kidney disease: a systematic review and meta-analysis.Semantic proximity Read ↗

ENPP1/PC-1 K121Q polymorphism and genetic susceptibility to type 2 diabetes in North Indians.Semantic proximity Read ↗

The ENPP1 K121Q polymorphism is not associated with type 2 diabetes in northern Chinese.Semantic proximity Read ↗

[The analysis of association between ENPP1 K121Q polymorphism and risk factors of type 2 diabetes mellitus in ukrainian population].Semantic proximity Read ↗

Role of ENPP1 Gene Variants in the Susceptibility to Diabetic Nephropathy in Patients with type 2 Diabetes Mellitus.Semantic proximity Read ↗

The role of K121Q ENPP1 polymorphism in diabetes mellitus and its complications.Semantic proximity Read ↗

The ENPP1 K121Q polymorphism is not associated with type 2 diabetes or obesity in the Chinese Han population.Semantic proximity Read ↗

New polymorphism of ENPP1 (PC-1) is associated with increased risk of type 2 diabetes among obese individuals.Semantic proximity Read ↗

No evidence for association of the ENPP1 (PC-1) K121Q variant with risk of type 2 diabetes in a Japanese population.Semantic proximity Read ↗

The ENPP1 K121Q polymorphism is associated with type 2 diabetes and related metabolic phenotypes in a Taiwanese population.Semantic proximity Read ↗

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