Article
Germ warfare in a microbial mat community: CRISPRs provide insights into the co-evolution of host and viral genomes.
PloS one - 1 Jan 2009
Heidelberg John F, Nelson William C, Schoenfeld Thomas, Bhaya Devaki
Abstract excerpt
CRISPR arrays and associated cas genes are widespread in bacteria and archaea and confer acquired resistance to viruses. To examine viral immunity in the context of naturally evolving microbial populations we analyzed genomic data from two thermophilic Synechococcus isolates (Syn OS-A and Syn OS-B') as well as a prokaryotic metagenome and viral metagenome derived from microbial mats in hotsprings at Yellowstone...
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