Back to search

Article

Quorum-sensing- and type VI secretion-mediated spatio-temporal cell death drives genetic diversity in <i>Vibrio cholerae</i>

2022-08-09

Abstract excerpt

<h4>Summary</h4> Bacterial colonies composed of genetically identical individuals can diversify to yield variant cells with distinct genotypes. Variant outgrowth manifests as sectors. Here, we show that Type 6 secretion system (T6SS)-driven cell death in Vibrio cholerae colonies imposes a selective pressure for the emergence of variant strains that can evade T6SS-mediated killing. T6SS-mediated cell death occurs...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
5b7d7efc-38a2-586b-a9a7-3cffe1fb2ef7
DOI
10.1101/2022.08.09.503374
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Quorum-sensing- and type VI secretion-mediated spatio-temporal cell death drives genetic diversity in <i>Vibrio cholerae</i>DOI 10.1101/2022.08.09.503374
Quorum-sensing- and type VI secretion-mediated spatiotemporal cell death drives genetic diversity in Vibrio cholerae.Semantic proximity
Analysis of <i>Vibrio cholerae</i> genomes using a novel bioinformatic tool identifies new, active Type VI Secretion System gene clustersSemantic proximity
A single nucleotide polymorphism determines constitutive versus inducible type VI secretion in <i>Vibrio cholerae</i>Semantic proximity
Type VI secretion system mutations reduced competitive fitness of classical Vibrio cholerae biotype.Semantic proximity
<i>Vibrio cholerae</i> Type VI Secretion System Auxiliary Cluster 3 is a Pandemic-associated Mobile Genetic ElementSemantic proximity
T6SS intraspecific competition orchestrates Vibrio cholerae genotypic diversity.Semantic proximity
Horizontal Gene Transfer of Functional Type VI Killing Genes by Natural Transformation.Semantic proximity
Multiple T6SSs, mobile auxiliary modules, and effectors revealed in a systematic analysis of the <i>Vibrio parahaemolyticus</i> pan-genomeSemantic proximity
Modular small RNA drives the emergence of virulence traits and environmental trade-offs in <i>Vibrio cholerae</i>Semantic proximity
Secreted Proteases Control the Timing of Aggregative Community Formation in <i>Vibrio cholerae</i>Semantic proximity
Single nucleotide polymorphism determines constitutive versus inducible type VI secretion in Vibrio cholerae.Semantic proximity
Allelic diversity uncovers protein domains contributing to the emergence of antimicrobial resistanceSemantic proximity
Select a neighboring publication to make it the new centre.