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Article

A role for common genomic variants in the assessment of familial breast cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Dec 2012

Sawyer Sarah, Mitchell Gillian, McKinley Joanne, Chenevix-Trench Georgia, Beesley Jonathan, Chen Xiao Qing, Bowtell David, Trainer Alison H, Harris Marion, Lindeman Geoffrey J, James Paul A

Abstract excerpt

PURPOSE: Genome-wide association studies have identified common genomic variants associated with increased susceptibility to breast cancer. In the general population, the risk associated with these known variants seems insufficient to inform clinical management. Their contribution to the development of familial breast cancer is less clear. PATIENTS AND METHODS: We studied 1,143 women with breast cancer who had...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23109704
DOI: 10.1200/JCO.2012.41.7469

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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