Article
Polygenes, risk prediction, and targeted prevention of breast cancer.
The New England journal of medicine - 26 Jun 2008
Pharoah Paul D P, Antoniou Antonis C, Easton Douglas F, Ponder Bruce A J
Abstract excerpt
BACKGROUND: New developments in the search for susceptibility alleles in complex disorders provide support for the possibility of a polygenic approach to the prevention and treatment of common diseases. METHODS: We examined the implications, both for individualized disease prevention and for public health policy, of findings concerning the risk of breast cancer that are based on common genetic variation. RESULTS:...
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