Androgen receptor association with mitotic chromatin - analysis with introduced deletions and disease-inflicting mutations.

Abstract excerpt

Sequence and structural anomalies in the gene for androgen receptor (AR) or its protein are associated with a range of clinical manifestations. Observations from living cells have shown that AR translocates to the nucleus upon ligand binding, where it forms typical 'nuclear foci' that are considered as sites of gene transcription. Recently, we reported the ligand-mediated association of AR with mitotic chromatin...

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