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Article

Age-related macular degeneration and coronary heart disease: evaluation of genetic and environmental associations.

European journal of medical genetics - 1 Feb 2013

Keilhauer Claudia N, Fritsche Lars G, Guthoff Rainer, Haubitz Imme, Weber Bernhard H

Abstract excerpt

An association between coronary heart disease (CHD) and age-related macular degeneration (AMD) has long been postulated but results from epidemiological case-control studies, and genetic analyses have been ambiguous. In this study we illuminate the association between AMD and CHD with respect to genetic and environmental risk factors, age of disease onset and AMD subgroups. AMD patients (n = 1036) and age-matched...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23103884
DOI: 10.1016/j.ejmg.2012.10.005

Genes

ARMS2
CFH
CFHR1
CFHR3

Variants

rs6677604
rs800292

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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