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Article

Genetic Risk, Lifestyle, and Age-Related Macular Degeneration in Europe: The EYE-RISK Consortium.

Ophthalmology - 1 Jul 2021

Colijn Johanna M, Meester-Smoor Magda, Verzijden Timo, de Breuk Anita, Silva Rufino, Merle Benedicte M J, Cougnard-Grégoire Audrey, Hoyng Carel B, Fauser Sascha, Coolen Anthonius, Creuzot-Garcher Catherine, Hense Hans-Werner, Ueffing Marius, Delcourt Cecile, den Hollander Anneke I, Klaver Caroline C W

Abstract excerpt

PURPOSE: Age-related macular degeneration (AMD) is a common multifactorial disease in the elderly with a prominent genetic basis. Many risk variants have been identified, but the interpretation remains challenging. We investigated the genetic distribution of AMD-associated risk variants in a large European consortium, calculated attributable and pathway-specific genetic risks, and assessed the influence of...

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Identifiers

PMID: 33253757
DOI: 10.1016/j.ophtha.2020.11.024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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