Article
Association analysis of ERCC5 gene polymorphisms with risk of breast cancer in Han women of northwest China.
Breast cancer (Tokyo, Japan) - 1 May 2016
Wang Haitao, Wang Tao, Guo Hongyun, Zhu Gongjian, Yang Suisheng, Hu Qingrong, Du Yanze, Bai Xiaorong, Chen Xuezhong, Su Haixiang
Abstract excerpt
BACKGROUND: ERCC5 plays an important role in DNA damage repair. Mutations in it will lead to DNA repair defects and genomic instability. Its functional single nucleotide polymorphisms (SNPs) may alter DNA repair capacity and affect cancer susceptibility. METHODS: This study aims to evaluate the association between SNPs in ERCC5 and breast cancer susceptibility in Han women subjects genetically from northwest...
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