Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Extramacular drusen are highly associated with age-related macular degeneration, but not with CFH and ARMS2 genotypes.

The British journal of ophthalmology - 1 Aug 2016

Ersoy L, Schick T, de Graft D, Felsch M, Hoyng C B, den Hollander A I, Kirchhof B, Fauser S, Liakopoulos S

Abstract excerpt

BACKGROUND: To evaluate the association of extramacular drusen (EMD) with age-related macular degeneration (AMD) and with complement factor H (CFH rs1061170) and age-related maculopathy susceptibility 2 (ARMS2 rs10490924) polymorphisms in individuals with and without AMD. METHODS: In this case-control study, AMD staging was performed in 622 individuals. EMD were defined as ≥10 drusen (including ≥1 intermediate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Complement Factor H
Share to Fluorescein Angiography
Share to Fundus Oculi
Share to Macular Degeneration
Share to Proteins
Share to Retina
Share to Retinal Drusen
Share to Tomography, Optical Coherence

Source

Identifiers

PMID: 26614632
DOI: 10.1136/bjophthalmol-2015-306806

Genes

EMD
ARMS2
CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Extramacular drusen are highly associated with age-related macular degeneration, but not with CFH and ARMS2 genotypes.PMID 26614632Read ↗

Genetic and environmental risk factors for extramacular drusen.Semantic proximity Read ↗

The contribution of genetic factors to phenotype and progression of drusen in early age-related macular degeneration.Semantic proximity Read ↗

Age-Related Macular Degeneration and Extramacular Drusen: Genetic Associations in the Coimbra Eye Study.Semantic proximity Read ↗

ARMS2 increases the risk of early and late age-related macular degeneration in the European Eye Study.Semantic proximity Read ↗

Association between Drusen Burden Determined by OCT and Genetic Risk in Early and Intermediate Age-Related Macular DegenerationSemantic proximity Read ↗

Association Between Perifoveal Drusen Burden Determined by OCT and Genetic Risk in Early and Intermediate Age-Related Macular Degeneration.Semantic proximity Read ↗

Association analysis of CFH and ARMS2 gene polymorphisms in a Brazilian cohort with age-related macular degeneration.Semantic proximity Read ↗

Polymorphisms in ARMS2/HTRA1 and complement genes and age-related macular degeneration in India: findings from the INDEYE study.Semantic proximity Read ↗

Small, hard macular drusen and peripheral drusen: associations with AMD genotypes in the Inter99 Eye Study.Semantic proximity Read ↗

How do genetic polymorphisms influence the efficacy of age-related macular degeneration treatments? A systematic review and meta-analysis.Semantic proximity Read ↗

Risk characteristics of the combined geographic atrophy and choroidal neovascularisation phenotype in age-related macular degeneration.Semantic proximity Read ↗

Genetics of Unilateral and Bilateral Age-Related Macular Degeneration Severity Stages.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.