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Article

Human Asunder promotes dynein recruitment and centrosomal tethering to the nucleus at mitotic entry.

Molecular biology of the cell - 1 Dec 2012

Jodoin Jeanne N, Shboul Mohammad, Sitaram Poojitha, Zein-Sabatto Hala, Reversade Bruno, Lee Ethan, Lee Laura A

Abstract excerpt

Recruitment of dynein motors to the nuclear surface is an essential step for nucleus-centrosome coupling in prophase. In cultured human cells, this dynein pool is anchored to nuclear pore complexes through RanBP2-Bicaudal D2 (BICD2) and Nup133- centromere protein F (CENP-F) networks. We previously reported that the asunder (asun) gene is required in Drosophila spermatocytes for perinuclear dynein localization and...

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Identifiers

PMID: 23097494
DOI: 10.1091/mbc.E12-07-0558
PMCID: PMC3521680

Genes

BICD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Human Asunder promotes dynein recruitment and centrosomal tethering to the nucleus at mitotic entry.PMID 23097494Read ↗

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