Article
Regulation of dynein localization and centrosome positioning by Lis-1 and asunder during Drosophila spermatogenesis.
Development (Cambridge, England) - 1 Aug 2012
Sitaram Poojitha, Anderson Michael A, Jodoin Jeanne N, Lee Ethan, Lee Laura A
Abstract excerpt
Dynein, a microtubule motor complex, plays crucial roles in cell-cycle progression in many systems. The LIS1 accessory protein directly binds dynein, although its precise role in regulating dynein remains unclear. Mutation of human LIS1 causes lissencephaly, a developmental brain disorder. To gai...
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