Article
Effect of the P450 oxidoreductase 28 polymorphism on the pharmacokinetics of tacrolimus in Chinese healthy male volunteers.
European journal of clinical pharmacology - 1 Apr 2013
Zhang Jing-Jing, Zhang Hua, Ding Xiao-Liang, Ma Sheng, Miao Li-Yan
Abstract excerpt
PURPOSE: To assess the influence of the P450 oxidoreductase 28 SNP (POR 28) on tacrolimus pharmacokinetics in the Chinese population. METHODS: Seventy-one healthy Chinese volunteers enrolled in the study received an oral dose of 2 mg of tacrolimus after providing written informed consent. CYP3A5...
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