Article
Efficacy of T cell depletion of surgically resected cadaveric marrows by monoclonal antibodies: considerations in HLA-mismatched marrow transplantation.
Progress in clinical and biological research - 1 Jan 1990
Gress R E, Bare C, Lucas P J, Cassel J, Nakamura H, Moses R D, Quinones R R
Abstract excerpt
The potential therapeutic benefits of allogeneic bone marrow transplantation (BMT) remain generally unavailable to patients who have diseases amenable to treatment by allogeneic BMT, but who lack an identifiable HLA-matched marrow donor. If graft versus host disease and graft rejection can be controlled, then the possibility of expanding allogeneic BMT to minimally HLA-matched or fully mismatched combinations...
Topics
- Antibodies, Monoclonal
- Bone Marrow
- Bone Marrow Cells
- Bone Marrow Transplantation
- Cadaver
- Complement System Proteins
- Female
- Fluoroimmunoassay
- HLA Antigens
- Humans