Article

Enabling MHC-mismatched hematopoietic stem cell transplants and organ graft tolerance without chemotherapy or radiation

2019-01-21

Abstract excerpt

<h4>Summary</h4> Hematopoietic stem cell (HSC) transplantation can replace diseased blood systems with a healthy one, thereby treating or curing genetic blood and immune disorders including autoimmune diseases and immunodeficiencies. However, toxic chemotherapy or radiation is necessary to ablate an animal’s existing blood system prior to HSC transplantation, leading to significant morbidity. To accomplish safer...

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Literature Corpus work: a658de9d-344c-5074-ba56-3c4efe568f8a
DOI: 10.1101/525899

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