Article
Mhc-DQB repertoire variation in hominoid and Old World primate species.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jul 1992
Otting N, Kenter M, van Weeren P, Jonker M, Bontrop R E
Abstract excerpt
Comparison of 87 distinct Mhc-DQB sequences, obtained from 13 primate species, demonstrates that five out of eight trans-species Mhc-DQB allele lineages are at least 30 million years old and predate divergence of hominoid and Old World primate species. One lineage may be much older because its me...
Topics
- Alleles
- Animals
- Base Sequence
- Biological Evolution
- Chromosome Mapping
- Codon
- Genes, MHC Class II
- HLA-DQ Antigens
- Molecular Sequence Data
- Mutation
- Primates
- Species Specificity