Evolutionary stability of transspecies major histocompatibility complex class II DRB lineages in humans and rhesus monkeys.

doi:10.1016/0198-8859(92)90092-2

Back to search

Article

Evolutionary stability of transspecies major histocompatibility complex class II DRB lineages in humans and rhesus monkeys.

Human immunology - 1 Sept 1992

Slierendregt B L, van Noort J T, Bakas R M, Otting N, Jonker M, Bontrop R E

Abstract excerpt

Sequence analysis of rhesus monkey (Macaca mulatta) polymorphic second exon of major histocompatibility complex class II DRB subregion genes demonstrates the existence of at least 34 alleles. Some of these rhesus monkey alleles are very similar (or nearly identical) to HLA-DRB alleles. These data...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Biological Evolution
HLA-DR Antigens
Humans
Macaca mulatta
Major Histocompatibility Complex
Molecular Sequence Data
Polymerase Chain Reaction

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.