Article
Insulin-like growth factor 1 (IGF1) polymorphism is associated with Alzheimer's disease in Han Chinese.
Neuroscience letters - 30 Nov 2012
Wang Wei, Yu Jin-Tai, Tan Lan, Liu Qiu-Yan, Wang Hui-Fu, Ma Xiao-Ying
Abstract excerpt
A review of pathogenic findings in Alzheimer's brains and the functional consequences of altered insulin-like growth factor 1 (IGF1) input to the brain suggest the association between Alzheimer's disease (AD) and the disrupted IGF1 signaling. Recently, the identification of polymorphism rs972936 that was associated with both an increased risk of AD and high circulating levels of IGF1 was reported in Southern...
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