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Article

Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles.

Gut - 1 Nov 2010

Tanaka Fumiaki, Yamamoto Ken, Suzuki Sadao, Inoue Hiroshi, Tsurumaru Masahiko, Kajiyama Yoshiaki, Kato Hoichi, Igaki Hiroyasu, Furuta Koh, Fujita Hiromasa, Tanaka Toshiaki, Tanaka Yoichi, Kawashima Yoshiyuki, Natsugoe Shoji, Setoyama Tetsuro, Tokudome Shinkan, Mimori Koshi, Haraguchi Naotsugu, Ishii Hideshi, Mori Masaki

Abstract excerpt

BACKGROUND: Oesophageal squamous cell carcinoma (OSCC) is considered a difficult cancer to cure. The detection of environmental and genetic factors is important for prevention on an individual basis. OBJECTIVE: To identify groups at high risk for OSCC by simultaneously analysing both genetic and environmental risk factors. Methods A multistage genome-wide association study of OSCC in Japanese individuals with a...

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Alcohol Dehydrogenase
Alcohol Drinking
Aldehyde Dehydrogenase
Aldehyde Dehydrogenase, Mitochondrial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Carcinoma, Squamous Cell

Cocarcinogenesis

Esophageal Neoplasms

Source

Identifiers

PMID: 20833657
DOI: 10.1136/gut.2009.205724

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Strong interaction between the effects of alcohol consumption and smoking on oesophageal squamous cell carcinoma among individuals with ADH1B and/or ALDH2 risk alleles.PMID 20833657Read ↗

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