Article
Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland.
Breast cancer research : BCR - 22 Oct 2012
Shehata Mona, Teschendorff Andrew, Sharp Gemma, Novcic Nikola, Russell I Alasdair, Avril Stefanie, Prater Michael, Eirew Peter, Caldas Carlos, Watson Christine J, Stingl John
Abstract excerpt
INTRODUCTION: The organisation of the mammary epithelial hierarchy is poorly understood. Our hypothesis is that the luminal cell compartment is more complex than initially described, and that an understanding of the developmental relationships within this lineage will help in understanding the cellular context in which breast tumours occur. METHODS: We used fluorescence-activated cell sorting along with in vitro...
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