Article
Epithelial progenitor cell lines as models of normal breast morphogenesis and neoplasia
1 Oct 2003
Abstract excerpt
The majority of human breast carcinomas exhibit luminal characteristics and as such, are most probably derived from progenitor cells within the luminal epithelial compartment. This has been subdivided recently into at least three luminal subtypes based on gene expression patterns. The value of knowing the cellular origin of individual tumours is clear and should aid in designing effective therapies. To do this,...
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