Article
A genetic variant in the gene encoding adrenomedullin predicts the development of dysglycemia over 6.4 years in Chinese.
Clinica chimica acta; international journal of clinical chemistry - 30 Jan 2011
Ong Kwok Leung, Tso Annette W K, Leung Raymond Y H, Cherny Stacey S, Sham Pak Chung, Lam Tai Hing, Cheung Bernard M Y, Lam Karen S L
Abstract excerpt
BACKGROUND: Adrenomedullin, a vasodilatory peptide, facilitates the differentiation of pre-adipocytes, and affects lipolysis and glucose uptake. We investigated the association of common single nucleotide polymorphisms (SNPs) in the gene encoding adrenomedullin (ADM) with dysglycemia in the Hong Kong Chinese population. METHODS: Four SNPs were genotyped in 1391 subjects without dysglycemia at baseline from the...
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