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Article

Relaxin regulates hyaluronan synthesis and aquaporins in the cervix of late pregnant mice.

Endocrinology - 1 Dec 2012

Soh Yu May, Tiwari Anjana, Mahendroo Mala, Conrad Kirk P, Parry Laura J

Abstract excerpt

Cervical ripening is associated with loss of structural integrity and tensile strength, thus enabling the cervix to dilate at term. It is characterized by changes in glycosaminoglycan composition, increased water content, and a progressive reorganization of the collagen network. The peptide hormone relaxin via interaction with its receptor, relaxin family peptide receptor 1 (RXFP1), promotes tissue hydration and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23087172
DOI: 10.1210/en.2012-1577
PMCID: PMC3512066

Genes

RXFP1
AQP3
AQP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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