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Article

Genotype MTBDRsl line probe assay shortens time to diagnosis of extensively drug-resistant tuberculosis in a high-throughput diagnostic laboratory.

American journal of respiratory and critical care medicine - 15 Dec 2012

Barnard Marinus, Warren Rob, Gey Van Pittius Nico, van Helden Paul, Bosman Marlein, Streicher Elizabeth, Coetzee Gerrit, O'Brien Richard

Abstract excerpt

RATIONALE: Conventional culture-based drug susceptibility testing (DST) for the second-line antituberculosis drugs is slow, leading to diagnostic delay with associated exacerbation of transmission, amplification of resistance, and increased mortality. OBJECTIVES: To assess the diagnostic performance of the GenoType MTBDRsl line probe assay (LPA) for the rapid detection of mutations conferring resistance to...

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Source

Identifiers

PMID: 23087027
DOI: 10.1164/rccm.201205-0960OC

Genes

DST
LPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genotype MTBDRsl line probe assay shortens time to diagnosis of extensively drug-resistant tuberculosis in a high-throughput diagnostic laboratory.PMID 23087027Read ↗

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