Article
Underestimation of the resistance of Mycobacterium tuberculosis to second-line drugs by the new GenoType MTBDRsl test.
The Journal of molecular diagnostics : JMD - 1 Jan 2013
Jin Jialin, Shen Yaojie, Fan Xiaoping, Diao Ni, Wang Feifei, Wang Sen, Weng Xinhua, Zhang Wenhong
Abstract excerpt
The GenoType MTBDRsl is a new-generation PCR-based line-probe assay for the detection of extensively drug-resistant tuberculosis (XDR-TB). This study evaluated the performance of MTBDRsl in detecting genotypic resistance to ethambutol, kanamycin, and ofloxacin in Mycobacterium tuberculosis (MTB) strains. The drug resistance of 262 unique clinical MTB isolates from China was analyzed with MTBDRsl, traditional TB...
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