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Article

Influence of functional polymorphisms in TNF-α, IL-8, and IL-10 cytokine genes on mRNA expression levels and risk of gastric cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2015

de Oliveira Juliana Garcia, Rossi Ana Flávia Teixeira, Nizato Daniela Manchini, Cadamuro Aline Cristina Targa, Jorge Yvana Cristina, Valsechi Marina Curado, Venâncio Larissa Paola Rodrigues, Rahal Paula, Pavarino Érika Cristina, Goloni-Bertollo Eny Maria, Silva Ana Elizabete

Abstract excerpt

Functional polymorphisms in promoter regions can produce changes in the affinity of transcription factors, thus altering the messenger ribonucleic acid (mRNA) expression levels of inflammatory cytokines associated with the risk of cancer development. The goal of this study was to evaluate the influence that polymorphisms in the cytokine genes known as TNF-α-308 G/A (rs1800629), TNF-α-857 C/T (rs1799724), IL-8-251...

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Source

Identifiers

PMID: 26088449
DOI: 10.1007/s13277-015-3593-x

Genes

TNF
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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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