Article
Polymorphisms in Th1-type cell-mediated response genes and risk of gastric cancer.
Carcinogenesis - 1 Jan 2007
Hou L, El-Omar E M, Chen J, Grillo P, Rabkin C S, Baccarelli A, Yeager M, Chanock S J, Zatonski W, Sobin L H, Lissowska J, Fraumeni J F, Chow W H
Abstract excerpt
Helicobacter pylori infection, the dominant risk factor for gastric cancers, has been shown to elicit T helper type 1 (Th1) polarized immunological responses. We conducted a population-based study of 305 gastric cancer cases and 427 age- and gender-matched controls in Warsaw, Poland, to evaluate the association with several variants in genes responsible for Th1-cell-mediated response. Genotyping was performed on...
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