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Article

Human leukocyte antigen DQ2.2 and celiac disease.

Journal of pediatric gastroenterology and nutrition - 1 Apr 2013

Mubarak Amani, Spierings Eric, Wolters Victorien, van Hoogstraten Ingrid, Kneepkens C M Frank, Houwen Roderick

Abstract excerpt

Patients with celiac disease (CD) lacking both human leukocyte antigen (HLA)-DQ2.5 in cis (DQA1*05:01, DQB1*02:01) or trans (DQA1*05:05, DQB1*02:02) configuration and HLA-DQ8 (DQA1*03:01, DQB1*03:02) are considered to be rare. Therefore, absence of these genotypes is commonly used to exclude the diagnosis of CD. To investigate whether this approach is justified, the HLA-distribution in 155 children with CD was...

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PMID: 23085892
DOI: 10.1097/MPG.0b013e31827913f9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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