Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common genetic variants in miR-1206 (8q24.2) and miR-612 (11q13.3) affect biogenesis of mature miRNA forms.

PloS one - 1 Jan 2012

Kim Hye Kyung, Prokunina-Olsson Ludmila, Chanock Stephen J

Abstract excerpt

Cancer genome-wide association studies (GWAS) have identified many common genetic markers located in non-coding regions of the genome. Two notable examples are the multi-cancer susceptibility regions, 8q24.2 and 11q13.3. Since these GWAS signals localize to gene-poor regions, we investigated genetic variants within pre-microRNA (pre-miRNA) transcripts as a possible link between the GWAS findings and the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to Cell Transformation, Neoplastic
Share to Chromosomes, Human, Pair 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 12

Share to Gene Expression Regulation, Neoplastic

Share to HapMap Project

Share to MicroRNAs

Share to Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 23077621
DOI: 10.1371/journal.pone.0047454
PMCID: PMC3471815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common genetic variants in miR-1206 (8q24.2) and miR-612 (11q13.3) affect biogenesis of mature miRNA forms.PMID 23077621Read ↗

microRNAs in Cancer Susceptibility.Semantic proximity Read ↗

Genetic polymorphisms and microRNAs: new direction in molecular epidemiology of solid cancer.Semantic proximity Read ↗

Epidemiological evidence for associations between variants in microRNA and cancer risk.Semantic proximity Read ↗

MicroRNAs and genomic variations: from Proteus tricks to Prometheus gift.Semantic proximity Read ↗

Single-nucleotide polymorphisms among microRNA: big effects on cancer.Semantic proximity Read ↗

Identification of diagnostic and prognostic biomarkers for cancer: Focusing on genetic variations in microRNA regulatory pathways (Review).Semantic proximity Read ↗

Classification of miRNA-related sequence variations.Semantic proximity Read ↗

Classification of heterogeneous genetic variations of microRNA regulome in cancer.Semantic proximity Read ↗

A catalog of polymorphisms falling in microRNA-binding regions of cancer genes.Semantic proximity Read ↗

Role of SNPs in the biogenesis of mature miRNAsSemantic proximity Read ↗

8q24.21 Locus: A Paradigm to Link Non-Coding RNAs, Genome Polymorphisms and Cancer.Semantic proximity Read ↗

Role of SNPs in the Biogenesis of Mature miRNAs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.