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Article

Role of SNPs in the Biogenesis of Mature miRNAs.

BioMed research international - 1 Jan 2021

Wang Ying, Ru Jidong, Meng Xianglian, Song Jianhua, Jiang Qingfeng, Li Shengqing, Jiang Jiulei, Li Yi

Abstract excerpt

Single nucleotide polymorphisms (SNPs) play a significant role in microRNA (miRNA) generation, processing, and function and contribute to multiple phenotypes and diseases. Therefore, whole-genome analysis of how SNPs affect miRNA maturation mechanisms is important for precision medicine. The present study established an SNP-associated pre-miRNA (SNP-pre-miRNA) database, named miRSNPBase, and constructed...

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Identifiers

PMID: 34239922
DOI: 10.1155/2021/2403418
PMCID: PMC8233088

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