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Article

Long-range transcriptional regulation of breast cancer genes.

Genes, chromosomes & cancer - 1 Feb 2013

Betts Joshua A, French Juliet D, Brown Melissa A, Edwards Stacey L

Abstract excerpt

Breast cancer is a major health problem and understanding the genetic basis of this disease is crucial for predicting risk and developing effective targeted therapeutics. Several breast cancer predisposing genes have been identified, but mutations in the coding regions of these genes only accounts for a small proportion of risk. Research now suggests that combinations of multiple non-coding changes in breast...

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Share to Regulatory Elements, Transcriptional
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23077082
DOI: 10.1002/gcc.22020

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