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Article

Association of a XRCC3 polymorphism and rectum mean dose with the risk of acute radio-induced gastrointestinal toxicity in prostate cancer patients.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Dec 2012

Fachal Laura, Gómez-Caamaño Antonio, Peleteiro Paula, Carballo Ana, Calvo-Crespo Patricia, Sánchez-García Manuel, Lobato-Busto Ramón, Carracedo Angel, Vega Ana

Abstract excerpt

BACKGROUND AND PURPOSE: We have performed a case-control study among prostate cancer patients treated with three-dimensional conformational radiotherapy (3D-CRT) in order to investigate the association between single nucleotide polymorphisms (SNPs), treatment and patient features with gastrointestinal and genitourinary acute toxicity. MATERIAL AND METHODS: A total of 698 patients were screened for 14 SNPs located...

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Source

Identifiers

PMID: 23075580
DOI: 10.1016/j.radonc.2012.09.013

Genes

XRCC3
ATM
ERCC2
LIG4
MLH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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