Article
Controlled angiogenesis in the heart by cell-based expression of specific vascular endothelial growth factor levels.
Human gene therapy methods - 1 Oct 2012
Melly Ludovic F, Marsano Anna, Frobert Aurelien, Boccardo Stefano, Helmrich Uta, Heberer Michael, Eckstein Friedrich S, Carrel Thierry P, Giraud Marie-Noëlle, Tevaearai Hendrik T, Banfi Andrea
Abstract excerpt
Vascular endothelial growth factor (VEGF) can induce normal angiogenesis or the growth of angioma-like vascular tumors depending on the amount secreted by each producing cell because it remains localized in the microenvironment. In order to control the distribution of VEGF expression levels in vivo, we recently developed a high-throughput fluorescence-activated cell sorting (FACS)-based technique to rapidly...
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