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Article

VEGF promotes cardiac stem cells differentiation into vascular endothelial cells via the PI3K/Akt signaling pathway.

Artificial cells, nanomedicine, and biotechnology - 1 Dec 2014

Xiao Nuan, Qi Xiao-Yong, Tang Lu-Ning, Tan Li-Li, Chen Ya-Qing, Zhao Hong-Mei

Abstract excerpt

Recent research suggested that cardiac stem cells (CSCs) may have the clinical application for cardiac repair. However, their characteristics and the regulatory mechanisms of their growth and differentiation have not been fully investigated. Vascular endothelial growth factor (VEGF, VEGF-A) is a major regulator of physiological and pathological angiogenesis. But the homing role of VEGF for CSCs is unclear. In...

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Identifiers

PMID: 24059532
DOI: 10.3109/21691401.2013.837473

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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