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Article

Racial and tissue-specific cancer risk associated with PARP1 (ADPRT) Val762Ala polymorphism: a meta-analysis.

Molecular biology reports - 1 Dec 2012

Pabalan Noel, Francisco-Pabalan Ofelia, Jarjanazi Hamdi, Li Hong, Sung Lillian, Ozcelik Hilmi

Abstract excerpt

The Val762Ala polymorphism poly [ADP-ribose] polymerase 1 (PARP1) gene [ADPRT (adenosine diphosphate ribosyltransferase) gene] affects enzymatic activity, which modulates cancer susceptibility among human populations. Individual data on 13,745 cases and 16,947 controls from 28 published case-control studies were re-evaluated. Odds ratios (OR) were estimated for ethnic group, cancer type, smoking joint effects and...

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Source

Identifiers

PMID: 23073772
DOI: 10.1007/s11033-012-2009-x

Genes

PARP1
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Racial and tissue-specific cancer risk associated with PARP1 (ADPRT) Val762Ala polymorphism: a meta-analysis.PMID 23073772Read ↗

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Correlation between PARP-1 Val762Ala polymorphism and the risk of lung cancer in a Chinese population.Semantic proximity Read ↗

PARP1 Val762Ala polymorphism reduces enzymatic activity.Semantic proximity Read ↗

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