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Article

Possible positive selection for an arsenic-protective haplotype in humans.

Environmental health perspectives - 1 Jan 2013

Schlebusch Carina M, Lewis Cecil M, Vahter Marie, Engström Karin, Tito Raúl Y, Obregón-Tito Alexandra J, Huerta Doris, Polo Susan I, Medina Ángel C, Brutsaert Tom D, Concha Gabriela, Jakobsson Mattias, Broberg Karin

Abstract excerpt

BACKGROUND: Arsenic in drinking water causes severe health effects. Indigenous people in the South American Andes have likely lived with arsenic-contaminated drinking water for thousands of years. Inhabitants of San Antonio de los Cobres (SAC) in the Argentinean highlands generally carry an AS3MT (the major arsenic-metabolizing gene) haplotype associated with reduced health risks due to rapid arsenic excretion...

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PMID: 23070617
DOI: 10.1289/ehp.1205504
PMCID: PMC3553437

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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