Article
iPS cell modeling of cardiometabolic diseases.
Journal of cardiovascular translational research - 1 Feb 2013
Nakamura Kenta, Hirano Ken-ichi, Wu Sean M
Abstract excerpt
Cardiometabolic diseases encompass simple monogenic enzyme deficiencies with well-established pathogenesis and clinical outcomes to complex polygenic diseases such as the cardiometabolic syndrome. The limited availability of relevant human cell types such as cardiomyocytes has hampered our ability to adequately model and study pathways or drugs relevant to these diseases in the heart. The recent discovery of...
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