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Article

Disease Modeling and Disease Gene Discovery in Cardiomyopathies: A Molecular Study of Induced Pluripotent Stem Cell Generated Cardiomyocytes.

International journal of molecular sciences - 24 Mar 2021

Kumar Satish, Curran Joanne E, Kumar Kashish, DeLeon Erica, Leandro Ana C, Peralta Juan, Williams-Blangero Sarah, Blangero John

Abstract excerpt

The in vitro modeling of cardiac development and cardiomyopathies in human induced pluripotent stem cell (iPSC)-derived cardiomyocytes (CMs) provides opportunities to aid the discovery of genetic, molecular, and developmental changes that are causal to, or influence, cardiomyopathies and related diseases. To better understand the functional and disease modeling potential of iPSC-differentiated CMs and to provide...

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Identifiers

PMID: 33805011
DOI: 10.3390/ijms22073311
PMCID: PMC8037452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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