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Article

The transporter ABCB7 is a mediator of the phenotype of acquired refractory anemia with ring sideroblasts.

Leukemia - 1 Apr 2013

Nikpour Maryam, Scharenberg Christian, Liu Anquan, Conte Simona, Karimi Mohsen, Mortera-Blanco Teresa, Giai Valentina, Fernandez-Mercado Marta, Papaemmanuil Elli, Högstrand Kari, Jansson Monika, Vedin Inger, Wainscoat James Stephen, Campbell Peter, Cazzola Mario, Boultwood Jacqueline, Grandien Alf, Hellström-Lindberg Eva

Abstract excerpt

Refractory anemia with ring sideroblasts (RARS) is characterized by mitochondrial ferritin (FTMT) accumulation and markedly suppressed expression of the iron transporter ABCB7. To test the hypothesis that ABCB7 is a key mediator of ineffective erythropoiesis of RARS, we modulated its expression i...

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Source

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Identifiers

PMID: 23070040
DOI: 10.1038/leu.2012.298
PMCID: PMC3794445

Genes

ABCB7
FTMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23070040-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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The transporter ABCB7 is a mediator of the phenotype of acquired refractory anemia with ring sideroblasts.PMID 23070040Read ↗

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