Refractory anemia with ring sideroblasts and RARS with thrombocytosis.

Abstract excerpt

DISEASE OVERVIEW: Ring sideroblasts (RS) are erythroid precursors with abnormal perinuclear mitochondrial iron accumulation. Two myeloid neoplasms defined by the presence of RS, include refractory anemia with ring sideroblasts (RARS) and RARS with thrombocytosis (RARS-T). DIAGNOSIS: RARS is a lower risk myelodysplastic syndrome (MDS) with dysplasia limited to the erythroid lineage, <5% bone marrow (BM) blasts and...

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• Anemia, Sideroblastic
• Angiogenesis Inhibitors
• Iron Overload
• Lenalidomide
• Receptors, Thrombopoietin