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Article

Deregulation of genes related to iron and mitochondrial metabolism in refractory anemia with ring sideroblasts.

PloS one - 1 Jan 2015

del Rey Mónica, Benito Rocío, Fontanillo Celia, Campos-Laborie Francisco J, Janusz Kamila, Velasco-Hernández Talía, Abáigar María, Hernández María, Cuello Rebeca, Borrego Daniel, Martín-Zanca Dionisio, De Las Rivas Javier, Mills Ken I, Hernández-Rivas Jesús M

Abstract excerpt

The presence of SF3B1 gene mutations is a hallmark of refractory anemia with ring sideroblasts (RARS). However, the mechanisms responsible for iron accumulation that characterize the Myelodysplastic Syndrome with ring sideroblasts (MDS-RS) are not completely understood. In order to gain insight i...

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Identifiers

PMID: 25955609
DOI: 10.1371/journal.pone.0126555
PMCID: PMC4425562

Genes

ALAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25955609-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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