Article
Biology of sideroblastic anemia.
[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Jan 2017
Harigae Hideo
Abstract excerpt
Sideroblastic anemia is characterized by anemia with ring sideroblasts produced by the bone marrow. Sideroblasts are formed by disutilization and deposit of iron in the mitochondoria. There are two forms of sideroblastic anemia: congenital and acquired. Congenital sideroblastic anemia is caused by mutations in genes involved in heme biosynthesis, iron-sulfur (Fe-S) cluster biogenesis, or mitochondrial metabolism....
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