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Article

Gene-gene interactions between interleukin-12A and interleukin-12B with the risk of brain tumor.

DNA and cell biology - 1 Feb 2012

Sima Xiutian, Xu Jianguo, Li Qiang, Luo Lin, Liu Jiangang, You Chao

Abstract excerpt

Emerging evidence from preclinical and clinical studies has shown that interleukin-12 (IL-12) has some effectiveness against endogenously arising brain tumor. The aim of this study was to investigate interactions of IL-12A and IL-12B polymorphisms on the risk of brain tumor. We analyzed IL-12A rs2243115 and IL-12B rs3212227 polymorphisms in 170 patients with brain tumor and 222 healthy controls in a Chinese...

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Identifiers

PMID: 22011063
DOI: 10.1089/dna.2011.1331

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