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Article

Interaction analysis of IL-12A and IL-12B polymorphisms with the risk of colorectal cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Dec 2015

Sun Ruifen, Jia Fu, Liang Yundan, Li Lijuan, Bai Peng, Yuan Fang, Gao Linbo, Zhang Lin

Abstract excerpt

IL-12 is an antitumor cytokine with functions of inhibiting tumor growth, invasion, and metastasis, indicating that IL-12 is a promising candidate for cancer treatment. The aim of this study was to investigate the association of IL-12A rs568408, IL-12A rs2243115, and IL-12B rs3212227 with the susceptibility to colorectal cancer (CRC). Two hundred and fifty-seven histopathologically confirmed CRC patients and 236...

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Identifiers

PMID: 26104769
DOI: 10.1007/s13277-015-3685-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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