Article
Genetics of emergent suicidality during antidepressive treatment--data from a naturalistic study on a large sample of inpatients with a major depressive episode.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jul 2013
Musil Richard, Zill Peter, Seemüller Florian, Bondy Brigitta, Meyer Sebastian, Spellmann Ilja, Bender Wolfram, Adli Mazda, Heuser Isabella, Fisher Robert, Gaebel Wolfgang, Maier Wolfgang, Rietschel Marcella, Rujescu Dan, Schennach Rebecca, Möller Hans-Jürgen, Riedel Michael
Abstract excerpt
Factors contributing to treatment-emergent suicidal ideation (TESI) using antidepressants have been in the focus of recent research strategies. We investigated previously established clinical predictors of TESI and combined these with several polymorphisms of candidate genes in patients with major depressive disorder. Common polymorphisms involved in the tryptophan hydroxylase 1 (TPH1) and 2 (TPH2), serotonin...
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