Article
STin2 variant and family history of suicide as significant predictors of suicide completion in major depression.
Biological psychiatry - 15 Jan 2006
Lopez de Lara Catalina, Dumais Alexandre, Rouleau Guy, Lesage Alain, Dumont Mimi, Chawky Nadia, Alda Martin, Benkelfat Chawki, Turecki Gustavo
Abstract excerpt
BACKGROUND: Suicide is the most serious outcome of major depression, yet not all depressed patients will commit suicide. Genes, along with other factors, might account for this difference. Serotonergic alterations have been observed in suicide and depression and impulsive-aggressive behaviors. Therefore, we aimed to identify predictors of suicide, considering genetic variation at the serotonin transporter (5-HTT)...
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